Ki67 expression in breast cancer

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Ki67 expression in breast cancer

ناطرس ىضرم يف Ki67 ةغبصل يعانلما روهظلا طنم مييقت :فادهلأا .Ki67 ل ةنكمم ةينهكت وأ ةيؤبنت ةميق يأ صحفو تايدوعسلا يدثلا Ki67 رشؤلم يمك مييقت فدهب تممص ةيداعتسا ةسارد هذه :ةقيرطلا ةيدوعس ةضيرم 115 نم يدثلا ماروأ تانيع يف يرثاكتلا )Ki67 PI( كللما ىفشتسم ،ىجولوثابلا مسقب 2015 سرامو رياني ينب تصخشُ ينب ةقلاعلا تطبرو .ةيدوعسلا ةيبرعلا ةكلملما ،ةرونلما ةنيدلما ،دهف ،ةيعانلما تاغبصلل ةكرتشلماو ةيدرفلا ج...

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Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group.

Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical assessment of the proportion of cells staining for the nuclear antigen Ki67 has become the most widely used method for comparing proliferation between tumor samples. Potential uses include prognosis, prediction of relative responsiveness or resistance to chemotherapy or endocrine therapy, estimation of res...

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New Insight into Ki67 Expression at the Invasive Front in Breast Cancer

PURPOSE To investigate the distribution of Ki67+ cells in breast cancer in relation to clinical-pathological parameters and prognosis. MATERIALS AND METHODS Ki67 expression status was detected in 1,086 breast cancer specimens using immunohistochemistry staining and examining the relationship between the Ki67+ cells' location. Subsequently, clinical-pathological parameters and prognosis were d...

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No increased Ki67 expression in ductal carcinoma in situ associated with invasive breast cancer.

Introduction Several studies indicate that ;50% of patients with positive biopsies for DCIS of the breast may develop invasive breast cancer within 1–24 years of diagnosis (1). The biological mechanisms involved in the progression of DCIS to invasive cancer are not fully understood. Although Ki67 labeling indices increased in invasive breast cancer (2, 3), there are limited data on this marker ...

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Relationship between NF-κB, ER, PR, Her2/neu, Ki67, p53 expression in human breast cancer.

AIM The aim of the present study was to investigate expression patterns of transcription factor NF-κB (p50 and p65), ER, PR, Her2/neu, Ki-67 and p53 in tumor tissue of patients with breast cancer (BC) and analyze correlation between these markers. PATIENTS AND METHODS 62 BC patients previously not treated with chemo- or radiotherapy were included in the study. All tumors belong to invasive du...

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ژورنال

عنوان ژورنال: Saudi Medical Journal

سال: 2016

ISSN: 0379-5284,1658-3175

DOI: 10.15537/smj.2016.2.12285